Blog and Knowledge Database
General
How Accurate Lactate Testing Can Improve Clinical Outcomes
Lactate—this word might bring back memories of high school chemistry or that burning sensation in your muscles after an intense workout. But lactate is more than just a byproduct of physical exertion; it’s a crucial biochemical player with significant implications in clinical medicine. In this article, we’re diving deep into
5 Common Stability Challenges in Lactate Sensors And How To Overcome Them
Ever wonder why lactate sensors are such a big deal? Whether you’re an athlete keeping tabs on your performance, a healthcare pro diagnosing conditions, or just a tech enthusiast, these little gadgets play a vital role. But here’s the thing: keeping them stable and reliable isn’t always a walk in
Interesting Facts About Enzymes And Their Role In Lactate Detection
Enzymes: Nature’s Biological Catalysts Imagine if you had a tiny superhero living inside you, tirelessly working around the clock to keep your body functioning smoothly. Well, guess what? You do! These superheroes are called enzymes, and they play a crucial role in just about every biological process that keeps us
Technology
Why Oxygen-Independent Enzyme Technology Simplifies In-Vivo Monitoring
Imagine if you could conduct complex biochemical reactions without relying on oxygen—a key player in many biological processes. Sound impossible? Well, thanks to advances in enzyme technology, this is becoming a reality. Enter the world of oxygen-independent enzymes, an exciting development that’s set to revolutionize biotechnology and medical diagnostics. Oxygen-Independent
The Benefits Of Using Additive-Free Enzyme Solutions In Diagnostics
Have you ever wondered why some diagnostic tests seem to hit the mark every time, while others can be a bit…well, off? The secret often lies in the enzymes used in these tests. These tiny powerhouses are the unsung heroes of modern diagnostics, driving the chemical reactions that help us
5 Common Stability Challenges in Lactate Sensors And How To Overcome Them
Ever wonder why lactate sensors are such a big deal? Whether you’re an athlete keeping tabs on your performance, a healthcare pro diagnosing conditions, or just a tech enthusiast, these little gadgets play a vital role. But here’s the thing: keeping them stable and reliable isn’t always a walk in
Science
Flavin Mononucleotide-Dependent l-Lactate Dehydrogenases: Expanding the Toolbox of Enzymes for l-Lactate Biosensors
The study explain the advantages of LDH Lactazymes, especially those on flavin mononucleotide (FMN)-dependent L-lactate dehydrogenases for biosensor applications. It investigates seven newly discovered enzymes for L-lactate detection and compares their performance to Aerococcus viridans LOx. The research emphasizes enzyme diversity in biosensors, focusing on enhancing sensitivity and stability for
Continuous Measurement of Lactate Concentration in Human Subjects through Direct Electron Transfer from Enzymes to Microneedle Electrodes
Microneedle biosensors modified with direct electron transfer enzymes were used to continuously monitor lactate levels in human interstitial fluid. The device was validated in a clinical study where lactate levels were altered through exercise. It operates at low voltage and correlates well with blood lactate concentrations, demonstrating potential for non-invasive
Detection of Lactate via Amperometric Sensors Modified With Direct Electron Transfer Enzyme Containing PEDOT:PSS and Hydrogel Inks
The study focuses on amperometric sensors modified with direct electron transfer (DET) Lactazymes from DirectSens for lactate detection in blood and interstitial dermal fluid. Two sensor types were developed: carbon-based screen-printed biosensors for rapid blood measurements and platinum-microneedle sensors for continuous, minimally invasive ISF monitoring. Both sensor types demonstrated effective